Pueraria montana & Pueraria lobata: In addition to genistein and daidzein, Pueraria provides additional isoflavones, such as daidzin, puerarin & 3'-methoxypuerarin. have provide other health benefits. Isoflavones from Pueraria lobata have the ability to diminish menopausal symptoms and support maintenance of bone mineral density. These non-soy isoflavones may also help protect the cardiovascular system, the nervous system, support the immune system function, inhibit angiogenesis, and protect against oxidative damage as antioxidants.
Red Clover Extract: (Trifolium pratense, stem, leaves, and flowers, standardized to 8% biochanins). In addition to genistein and daidzein, Trifolium pratense (Red Clover) provides other isoflavones such as biochanin A, & formononetin, which provide additional health benefits.
Isoflavones from red clover (Trifolium pretense) have the ability to diminish menopausal symptoms and support maintenance of bone mineral density. Red clover also protects the cardiovascular system, supports the immune system, inhibit angiogenesis, and protects against oxidative damage.
Bacopa Extract: (Bacopa monnieri, aerial parts, standardized to 20% bacosides) Bacopa is used as a brain tonic to enhance memory and considered valuable for the aging brain. It is also used to promote longevity, to treat nervous breakdowns and exhaustion and recover from nervous deficits due to injury or stroke. While enhancing brain function it also has a mildly sedative and tranquilizing effect and can help treat insomnia. Bacopa is a functional mimetic of estrogen that also to help the body adapt to both acute and chronic stress. It does not bind to estrogen receptors.
Gotu Kola Extract: (Centella asiatica, leaf, standardized to 10% asiaticosides)
Gotu kola is used to improve memory and cognitive function. It is beneficial for both memory improvement and neuroprotection. Centella improves antioxidant function by increasing the activity of mitochondrial antioxidant enzymes (SOD, CAT, GSH, & GPx) as well as supporting the actions of nutrient antioxidants such as vitamin C and beta-carotene. Centella also has anti-cancer properties and can provide protection form microvascular disease.
Hops Extract: (Humulus lupulus, strobiles, standardized to 5% alpha bitter acids) Some of the compounds occurring naturally in hops, such as 8-prenylnaringenin (8-PN), have very strong phytoestrogenic activity that can reduce hot flashes in menopausal women effectively improve mood disturbances such as restlessness, anxiety, as well as sleep disturbances. Research has demonstrated that 8-PN has a preventive effect against breast and ovarian cancer. Hops also has sedative effects and can be used to reduce anxiety and irritability, or help induce sleep.
Dong Quai: (Angelica sinensis, root extract,standardized to 1% ligustilides) Dong Quai has phytoestrogen activity to decrease the symptoms of menopause. It has no estrogen action and does not produce estrogen-like responses in endometrial thickness, so may be considered safe for women who need to avoid estrogens. It helps increase vaginal lubrication and increase sexual activity. The ferulic acid in Don Quai increases bone formation differently from estrogens, so it is a functional mimetic of estrogen. It is also antioxidant antiinflammatory, anti-allergy and anti-tumor.
Schizandra Fruit Extract: (Schizandra chinensis, standardized to 9% schisandrins) Schisandra may act as a functional mimetic of estrogen with SERM qualities. It has anti-proliferative properties for estrogen sensitive tissue, but is cardioprotective, neuroprotective and has been traditionally been used to treat fatigue and spontaneous sweating. Its adaptogenic actions appear to influence the brain the most. This herb is used for decreased nervous system function, especially due to estrogen deficiency. It improves concentration, coordination, vision, hearing and sense of touch.
Sage Leaf: (Salvia officinalis) Sage contains phytoestrogen-like substances that make it useful to treat a wide range of menopausal symptoms including hot flashes and mood swings due to hormone changes. Sage can effectively be used to decrease perspiration in both daytime and night-time excessive sweating. The positive effects of Sage on the nervous system include both memory improving properties and calming actions, the latter of which have been attributed to its ability to bind to the GABA/benzodiazepine receptor complex in brain tissue.
Black Cohosh Extract: (Cimicifuga racemosa, root and stem, standardized to 8% triterpene glycosides) Black Cohosh decreases hot flushes and other symptoms of menopausal discomfort. The actions of Cimicifuga do not stimulates uterine tissues the way estrogen does, so it lacks the complete properties of estrogen. It can increase blood flow to the pelvic area, and relieve spasms, cramps & inflammation. Black Cohosh has a mild mood elevating effect and decreases menopause related depression. It may have SERM activity specific to bone and hypothalamo/pituitary tissues.